Author

Zissis C. Chroneos

Pennsylvania State UniversityORCID 0000-0002-9841-7917Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Edward William HarhajiD· 2 shared Adolfo García-Sastre· 1 shared Andrew S PekosziD· 1 shared Arun KapooriD· 1 shared Christopher C. NorburyiD· 1 shared Jiawen ZhangiD· 1 shared John Tawil· 1 shared Julie C. Fanburg–SmithiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Edward William HarhajORCID

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2 papers

Recent·Most cited

The aryl hydrocarbon receptor interacting protein suppresses RNA virus-induced type I IFN and IL-6 in mouse macrophages

Sarah A. Kazzaz, Todd M. Umstead, Zissis C. Chroneos, Edward William Harhaj

This study shows that AIP suppresses type I IFN and IL-6 production in mouse macrophages during RNA virus infection by regulating IRF7 degradation.

bioRxiv · Jun 30, 2025 · PreprintImmunology

ZFAND6 is a subunit of a TRAF2-cIAP E3 ubiquitin ligase complex essential for mitophagy

Kashif Shaikh, Melissa Bowman, Sarah M. McCormick, Linlin Gao, Jiawen Zhang, John Tawil, Arun Kapoor, Ravit Arav‐Boger, Young Bong Choi, Andrew S Pekosz, Sabra L. Klein, Matthew Lanza, Julie C. Fanburg–Smith, Adolfo García-Sastre, Christopher C. Norbury, , Edward William Harhaj

This study identifies ZFAND6 as a component of a TRAF2-cIAP E3 ubiquitin ligase complex that regulates mitophagy, maintaining mitochondrial homeostasis and influencing immune responses to viral infection.

iScience · Dec 6, 2024Peer-reviewedImmunology