Author

Cristina Roseti

University of InsubriaORCID 0000-0002-9863-0371Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Angela Di IacovoiD· 2 shared Elena BossiiD· 2 shared Laura CivieroiD· 2 shared Ludovica IovinoiD· 2 shared Algerta MarkuiD· 1 shared Antonella MarteiD· 1 shared Carla PeregoiD· 1 shared Charlotte Kilstrup‐NielseniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersNeuroscience

Angela Di IacovoORCID

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2 papers

Recent·Most cited

LRRK2 G2019S disrupts GABAergic signaling and shifts excitatory/inhibitory balance in the striatum

Angela Di Iacovo, Giuseppe Aceto, Ludovica Iovino, Roberta De Rosa, Raffaella Cinquetti, Charlotte Kilstrup‐Nielsen, Tiziana Alberio, Marcello D’Ascenzo, Laura Civiero, Elena Bossi, Cristina Roseti

This paper shows that the LRRK2 G2019S mutation reduces GABA-evoked currents and disrupts the excitatory/inhibitory balance in the striatum.

bioRxiv · Oct 23, 2025 · PreprintNeuroscience

Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson's disease

Ludovica Iovino, Veronica Giusti, Francesca Pischedda, Elena Giusto, Nicoletta Plotegher, Antonella Marte, Ilaria Battisti, Angela Di Iacovo, Algerta Marku, Giovanni Piccoli, Rina Bandopadhyay, Carla Perego, Tiziana Bonifacino, Giambattista Bonanno, Cristina Roseti, , Laura Civiero

This study shows that the LRRK2 G2019S mutation impairs EAAT2 trafficking, leading to reduced glutamate clearance and potential neurodegeneration in Parkinson's disease.

Acta Neuropathologica · May 21, 2022Peer-reviewedNeuroscience