José M.A. Moreira

Antimicrobial and Cytotoxic Lysolipins I-M Isolated from Streptomyces sp. P8-2B18

This study isolates and characterizes new lysolipin analogues from Streptomyces sp. P8-2B18, revealing structural diversity and varying bioactivities against bacteria, fungi, and cancer cells.

Discovery and Biosynthesis of Nyuzenamides D and E by Genome Mining in Streptomyces hygroscopicus

The paper identifies and confirms the biosynthetic gene cluster for nyuzenamides D and E in Streptomyces hygroscopicus through genome mining and experimental validation.

Maramycin, a cytotoxic isoquinolinequinone terpenoid produced through heterologous expression of a bifunctional indole prenyltransferase /tryptophan indole-lyase in S. albidoflavus

The paper reports the discovery of maramycin, a novel isoquinolinequinone alkaloid produced through heterologous expression of a bifunctional enzyme in Streptomyces albidoflavus, showing moderate cytotoxicity against prostate cancer cells.

A streamlined mass spectrometry-based proteomics workflow forlarge scale FFPE tissue analysis

This paper presents a streamlined mass spectrometry-based proteomics workflow for analyzing FFPE tissue samples, demonstrating efficient and scalable proteome profiling of clinical specimens.