Author

Pawel Swietach

University of OxfordORCID 0000-0002-9945-9473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Aarif SiddiquiiD· 1 shared Adriana Martinez-TurtosiD· 1 shared Aiswarya Dev· 1 shared Alexander D. CorbettiD· 1 shared Andreas KoschinskiiD· 1 shared Anne Mette Askehøj RømeriD· 1 shared Annika WinboiD· 1 shared Anthony GalioneiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

Aarif SiddiquiORCID

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2 papers

Recent·Most cited

Lysosomal signaling pathways influence heart rhythm, and regulate atrial function

Emily Akerman, Rebecca A.B. Burton, Eva A. Rog‐Zielinska, Annika Winbo, Daniel Aston, Florian Falter, R. B. A. Mu-u-min, Matthew J. Read, Samuel J. Bose, Pawel Swietach, Jingyu Wang, Alexander D. Corbett, Andreas Koschinski, Serena Calamaio, Dario Melgari, , Derek A. Terrar

This study investigates the role of lysosomal Ca2+ signaling in heart rhythm and atrial function, finding that NAADP pathway inhibition affects SAN pacemaker activity and cAMP production in atrial myocytes.

Cardiovascular Research · Sep 19, 2026Peer-reviewedPhysiology

Contact-based thymidylate transfer promotes collective tumor growth

Aarif Siddiqui, Anne Mette Askehøj Rømer, Luisa Pinna, Vignesh Ramesh, Sarah Søgaard Møller, Paradesi Naidu Gollavilli, Adriana Martinez-Turtos, Steffi Varghese, Lærke B. Guldborg, Nagendra Prasad Palani, Francesca Napoli, Marco Volante, Luis Córdova Bahena, Marco Velasco, Kumar Somyajit, , Paolo Ceppi

The paper identifies a mechanism where dTMP equilibration via gap junctions enables collective tumor growth in cells lacking canonical dTMP synthesis.

bioRxiv · Jul 31, 2024 · PreprintCancer Biology