Glycoengineering of extracellular vesicles enhances cellular uptake and cargo delivery to target cells
Weihua Tian, Jiasi Chen, Anne Louise Blomberg, Judit Pina Agullet, Albert Juan Fuglsang-Madsen, Asha M. Rudjord-Levann, Helle Krogh Johansen, Søren Molin, Lasse Ebdrup Pedersen, Steffen Goletz
This study shows that removing glycosaminoglycans from extracellular vesicles increases their uptake and cargo delivery to target cells, suggesting glycan structures can be tuned for better drug delivery.
bioRxiv · Mar 23, 2026 · PreprintBioengineering