Steffen Goletz

This study identifies BNIP3L/NIX-mediated mitophagy as a critical pathway that limits Alzheimer's disease pathology and preserves neuronal function by maintaining mitochondrial health and reducing proteotoxicity.

This study develops GM1-receptor-mimic probiotic bacteria that bind and sequester cholera toxin B subunit in vitro, reducing its binding to host cells.

This paper develops a single-domain antibody specific for M1-linked ubiquitin chains, enabling their detection and analysis across multiple applications.

This study shows that removing glycosaminoglycans from extracellular vesicles increases their uptake and cargo delivery to target cells, suggesting glycan structures can be tuned for better drug delivery.

This study investigates how glycan structures affect GM-CSF bioactivity by engineering glycoforms in Chinese hamster ovary cells and testing their effects on TF-1 cell proliferation.

This paper introduces AbTags, a method to enhance detection of low-abundant proteins in single-cell proteomics by mass spectrometry through antibody-based signal amplification.

The paper investigates dermokine's role in keratinocyte adhesion through multi-omics analysis, showing that dermokine loss increases p120 phosphorylation and reduces cell-cell adhesion.