Author

Julie Urgiles

Broad InstituteORCID 0000-0002-9967-0623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Amruth Kumar· 1 shared André Richters· 1 shared Angela N. KoehleriD· 1 shared Ann-Sophie Koglin· 1 shared Charles A. WhittakeriD· 1 shared Christopher J. OttiD· 1 shared Drew A. HarrisoniD· 1 shared Eliezer CaloiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Amruth Kumar

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1 paper

Recent·Most cited

Cancer BiologyCell chemical biologyPeer-reviewedMar 29, 2025

Targeted Degradation of CDK9 Potently Disrupts the MYC Transcriptional Network

Mohammed A. Toure, Keisuke Motoyama, Yichen Xiang…·Angela N. Koehler

This study shows that CDK9 degradation with KI-CDK9d-32 is more effective than inhibition in disrupting MYC transcriptional networks and causes MYC downregulation and nucleolar destabilization.

22 citationstop 3%

humanproteomics

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