Author

Amruth Kumar

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

André Richters· 1 shared Angela N. KoehleriD· 1 shared Ann-Sophie Koglin· 1 shared Charles A. WhittakeriD· 1 shared Christopher J. OttiD· 1 shared Drew A. HarrisoniD· 1 shared Eliezer CaloiD· 1 shared Florian KabingeriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

André Richters

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1 paper

Recent·Most cited

Targeted Degradation of CDK9 Potently Disrupts the MYC Transcriptional Network

Mohammed A. Toure, Keisuke Motoyama, Yichen Xiang, Julie Urgiles, Florian Kabinger, Ann-Sophie Koglin, Ramya S. Iyer, Kaitlyn Gagnon, Amruth Kumar, Samuel Ojeda, Drew A. Harrison, Matthew G. Rees, Jennifer A. Roth, Christopher J. Ott, Richard P. Schiavoni, , Angela N. Koehler

This study shows that CDK9 degradation with KI-CDK9d-32 is more effective than inhibition in disrupting MYC transcriptional networks and causes MYC downregulation and nucleolar destabilization.

Cell chemical biology · Mar 29, 2025Peer-reviewedCancer Biology