Author

Florence E. Layburn

University of AucklandORCID 0000-0002-9986-4655Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Adelie Y. S. Tan· 1 shared Annelies QuaegebeuriD· 1 shared Caroline H. Williams‐GrayiD· 1 shared Daniel Rodgers· 1 shared David KlenermaniD· 1 shared Dorothea BökeniD· 1 shared George NolaniD· 1 shared Hilal Ahmed LashueliD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Adelie Y. S. Tan

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Nanoscopic tau aggregates in Parkinson's disease

Florence E. Layburn, Dorothea Böken, Yu Zhang, Kristy Halliday, Daniel Rodgers, Shekhar Kedia, George Nolan, Lakmini Kahanawita, Patel Bd, Annelies Quaegebeur, Caroline H. Williams‐Gray, David Klenerman

This study uses SiMPull to detect nanoscopic tau aggregates in PD brain regions, finding high-intensity aggregates in some PD cases despite negative IHC results.

npj Parkinson s Disease · Jul 27, 2026Peer-reviewedNeuroscience

N-terminal mutant Huntingtin deposition correlates with CAG repeat length and disease onset, but not neuronal loss in Huntington's disease

Florence E. Layburn, Adelie Y. S. Tan, Nasim F. Mehrabi, Maurice A. Curtis, Lynette J. Tippett, Nathan Riguet, Lorène Aeschbach, Hilal Ahmed Lashuel, Mike Dragunow, Richard L. M. Faull, Malvindar K. Singh‐Bains

This study screens antibodies against huntingtin (Htt) to analyze Htt distribution and aggregates in HD brain tissue, finding correlations between CAG repeat length and Htt aggregation, but not neuronal loss.

bioRxiv · May 3, 2022 · PreprintNeuroscience