Author

Malvindar K. Singh‐Bains

University of AucklandORCID 0000-0002-6634-1751Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Hilal Ahmed LashueliD· 3 shared Maurice A. CurtisiD· 3 shared Richard L. M. FaulliD· 3 shared Adelie Y. S. Tan· 2 shared Lynette J. TippettiD· 2 shared Mike DragunowiD· 2 shared Anass ChikiiD· 1 shared Andrea CaricasoleiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Hilal Ahmed LashuelORCID

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3 papers

Recent·Most cited

NeuroscienceScientific ReportsPeer-reviewedMay 3, 2025

Huntingtin inclusion bodies have distinct immunophenotypes and ubiquitination profiles in the Huntington's disease human cerebral cortex

Molly E. V. Swanson, Adelie Y. S. Tan, Lynette J. Tippett…·Malvindar K. Singh‐Bains

This study examines the immunophenotypic and ubiquitination diversity of Huntingtin inclusion bodies in Huntington's disease cerebral cortex, revealing heterogeneity in composition and degradation pathways.

5 citations

humanimaging

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NeurosciencebioRxivPreprintMay 3, 2022

N-terminal mutant Huntingtin deposition correlates with CAG repeat length and disease onset, but not neuronal loss in Huntington's disease

Florence E. Layburn, Adelie Y. S. Tan, Nasim F. Mehrabi…·Malvindar K. Singh‐Bains

This study screens antibodies against huntingtin (Htt) to analyze Htt distribution and aggregates in HD brain tissue, finding correlations between CAG repeat length and Htt aggregation, but not neuronal loss.

DOI 10.1101/2022.05.03.490349

humanprotein sequence

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NeurosciencebioRxivPreprintDec 10, 2019

TBK1 regulates autophagic clearance of soluble mutant huntingtin and inhibits aggregation/toxicity in different models of Huntington's disease

Ramanath Narayana Hegde, Anass Chiki, Lara Petricca…·Hilal Ahmed Lashuel

This study identifies TBK1 as a kinase that phosphorylates mutant huntingtin, reduces its aggregation and toxicity in multiple HD models.

2 citations

C. eleganshuman

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