Author

Shengtao Yang

Yale UniversityORCID 0000-0002-9997-5427Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:non-human primate· 1

Frequent Co-Authors

Amy F.T. ArnsteniD· 1 shared Athena May· 1 shared David A. LewisiD· 1 shared Dibyadeep DattaiD· 1 shared Elizabeth WooiD· 1 shared Emi LingiD· 1 shared Fenna M. KrieneniD· 1 shared George AndersoniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Amy F.T. ArnstenORCID

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1 paper

Recent·Most cited

Kynurenic acid inflammatory signaling expands in primates and impairs prefrontal cortical cognition

Shengtao Yang, Dibyadeep Datta, Fenna M. Krienen, Emi Ling, Elizabeth Woo, Athena May, George Anderson, Veronica C. Galvin, Guillermo González‐Burgos, David A. Lewis, Steven A. McCarroll, Amy F.T. Arnsten, Min Wang

This study shows that kynurenic acid (KYNA) and its enzyme KAT II expand in primate dlPFC, impairing cognitive functions by affecting NMDA and nic-7Rs, and suggests targeting KYNA as a therapeutic approach for neuroinflammatory disorders.

bioRxiv · Jun 13, 2024 · PreprintNeuroscience