Esther Serrano‐Saiz

The paper identifies a signaling network motif where dimerization-linked nucleocytoplasmic shuttling couples protein expression levels with intracellular localization, modulating signaling cascade activity.

This study identifies MT4-MMP as a regulator of NRP1 shedding, which modulates VEGFA signaling during embryonic brain angiogenesis and wound repair.

This study creates an expression atlas of Dmrt genes in the mouse brain, revealing their expression patterns and potential roles in sexual differentiation and neural circuit development.

This study shows Dmrt2 regulates sex-biased neuronal development in the cingulate cortex of mice, affecting proliferation, migration, and gene expression.

This study shows that Nrp1 gradient regulates late postnatal branching and refinement of callosal projections in the somatosensory cortex, determining homotopic and heterotopic connectivity.

The paper identifies a regulatory pathway controlling the timing of sexual differentiation in C. elegans and shows its conservation in mice and humans.

The paper identifies dmd-3 as a conserved transcription factor controlling sex-specific differentiation of PHC neurons in C. elegans through cell-autonomous mechanisms.