Jonathon Howard

This paper introduces OpenFLR, a software framework for real-time volumetric reconstruction and calcium imaging using Fourier light-field microscopy in Hydra.

The paper introduces a Discard-and-Restart MD algorithm to efficiently sample protein transition states, enhancing structure-based drug discovery by reducing simulation times by up to 2000x.

The paper develops a mean-field model showing stochastic growth can create complex dendritic arbors without external guidance.

The paper investigates how Rab4 signaling via PI(3)P regulates endosomal trafficking and synaptic remodeling during development in Drosophila larvae.

This study shows insulin signaling increases Rab4 vesicle transport in axons by recruiting Klp98A via Vps34-PI3Kinase activation in Drosophila.

The paper develops a combined microscope platform that integrates quantitative phase contrast and super-resolution fluorescence imaging for high-sensitivity visualization of sub-cellular structures and molecules in their cellular context.

This study uses laser stimulation to show that Drosophila Class IV nociceptors have two distinct pathways for mechanical stimulus detection: direct dendritic contact and non-contact via diffusible molecules.

The paper measures the energetic costs of early zebrafish embryogenesis and finds that heat dissipation scales with plasma membrane maintenance rather than cell number.