Rui Shao

The paper uses pooled overexpression screens to identify PIPPI, a novel microprotein involved in the ER stress response, by screening sORFs for cytoprotective effects against 6-thioguanine.

This study uses CUT&Tag to map G-quadruplex structures in mammalian cells, revealing their genomic distribution and relationship with transcription and R loops.

This study uses TT-seq to analyze RNA synthesis dynamics in three mouse pluripotent states, finding reduced RNA synthesis and elongation velocity in 2i and mTORi states.