Alexander Woglar

The paper investigates the timing and mechanism of crossover designation in C. elegans using advanced imaging techniques, revealing a multi-step, dynamic regulation process.

This study shows SAS-1 is essential for centriole integrity and ciliary function in C. elegans and interacts with SSNA-1 to maintain these structures.

This study identifies mechanisms by which Naegleria gruberi eliminates axonemes and centrioles during life cycle reversion, revealing lysosomal and proteasome-dependent pathways and extracellular shedding.

This study investigates the distinct roles of RAD-54.L and RAD-54.B in C. elegans meiotic prophase, showing RAD-54.L facilitates RAD-51 removal while RAD-54.B prevents excessive RAD-51 accumulation.

The paper identifies DSB-3 as a meiotic DSB-promoting protein in C. elegans, showing both conservation with and divergence from homologous complexes in other organisms.

This study identifies the HAL-2/HAL-3 complex as essential for regulating Polo-like kinase activity during C. elegans meiosis, ensuring proper homolog pairing and synaptonemal complex assembly.

This study shows that meiotic recombination modulates the stability of the synaptonemal complex in C. elegans, with PLK-2 playing a key role in this process.