PathologybioRxivPreprint
Diet-induced MASH liver fibrosis promoted by EphB2 can be targeted by small molecule tetramerization inhibitors
Masaaki Yoshigi, Séverin Donald Kamdem, Hanghang Wang…·Patrice Nsangou Mimche
This study identifies EphB2 as a driver of MASH liver fibrosis and shows that targeting EphB2 with small molecule inhibitors can reduce fibrosis in mouse models.