Author
Saarland UniversityORCID 0000-0003-0205-3678Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Isabel Stötzel, Ann-Kathrin Weier, Apurba Sarkar…·Eva Kiermaier
This study shows that multiple clustered centrosomes in antigen-presenting cells enhance T cell activation by positioning near the cell center, unlike T cells where centrosomes polarize toward the immune synapse.
Jona Causemann, Barbara Schmidt, Daniel Granz…·Robert Ernst
The paper investigates how Mga2 converts membrane physical cues into biochemical outputs via ubiquitylation, revealing a signal amplification mechanism involving E3 ligase autoubiquitylation.
Pinaki Nayak, Anil Kumar Dasanna, Raja Paul, Heiko Rieger
The paper develops a computational model of actin-microtubule crosstalk in migrating cells, showing how microtubule dynamics influence cell shape, migration direction, and responses to obstacles.
Barbara Schmidt, Ivan Bogeski, Barbara A. Niemeyer, Heiko Rieger
The paper uses a reaction-diffusion model to analyze STIM1-ORAI1 interactions in CRAC channel formation, showing how ROS inhibition affects Ca2+ influx and channel configuration preferences.