Young-Suk Lee

The paper identifies alternative polyadenylation as a key mechanism by which inverted Alu repeats regulate gene expression and contribute to disease.

This study identifies FTO's role in regulating multiple WNT signaling pathways, revealing its impact on canonical and noncanonical WNT signaling through RNA demethylation and DKK1 upregulation.

The paper identifies dsRNA-binding proteins that mediate decitabine's effects by stabilizing ERV RNAs, showing low Stau1 and TINCR expression correlates with poor treatment outcomes in AML patients.