Hector Martinez‐Navarro

This paper develops sex-specific human electromechanical models to simulate and evaluate sex differences in drug responses and ECG biomarkers, revealing ionic and anatomical mechanisms underlying these differences.

T-World is a computational model of human ventricular myocytes that accurately replicates physiological processes and identifies arrhythmia risks, with applications in drug response prediction.

The paper uses in-silico trials to evaluate the efficacy of SK and K2P channel block in atrial fibrillation, finding that combined block significantly improves cardioversion success.

The paper uses human-based modeling to evaluate cell therapy in acute and chronic myocardial infarction, finding that cell heterogeneity and Purkinje system function influence arrhythmia risk.