Author
University of ExeterORCID 0000-0003-0271-9636Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Joseph Westley, Tatiana Dimitriu, Andrew Matthews…·Stineke van Houte
The paper shows that diversity in restriction-modification systems is maintained through trade-offs between defense strength and horizontal transferability, and provides collective protection against phages.
Meaghan Castledine, Zuzanna Szczutkowska, Andrew Matthews…·Angus G. J. Buckling
This study shows macrophages reduce bacteriophage efficacy and increase bacterial resistance in Pseudomonas aeruginosa during phage therapy.
Andrew Matthews, Tatiana Dimitriu
The paper shows that plasmids can evolve to lose antibiotic resistance genes, becoming stealthier and more transmissible, leading to AMR extinction in bacterial populations.