Diego Javier Páez-Moscoso

The paper uses atomistic simulations to study contact dynamics in MUT-16 condensates, finding short-lived contacts and identifying key interactions and factors influencing condensate behavior.

The paper identifies a novel regulatory mechanism involving proteolytic processing of N-terminal intrinsically disordered regions in C. elegans Argonaute proteins, which controls small RNA selectivity and activity.

This study uses multiscale simulations to investigate MUT-16 phase separation and its role in recruiting MUT-8, confirming key interactions through in vitro experiments.

The paper identifies two new proteins, Thc1 and Bmc1, that function with Pof8 in telomerase biogenesis by recognizing folded telomerase RNA and facilitating complex assembly.