Author

Ida J. Isolehto

Institute of Molecular BiologyORCID 0000-0001-9322-7586Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:metagenomics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

René F. KettingiD· 3 shared Fridolin KielischiD· 2 shared Ann‐Sophie SeistrupiD· 1 shared Brooke E Montgomery· 1 shared Catherine S. SharpiD· 1 shared Colin N Magelky· 1 shared Diego Javier Páez-MoscosoiD· 1 shared Dustin L. UpdikeiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMolecular Biology

René F. KettingORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintDec 21, 2025

Proteolytic Control of an Auto-inhibitory Intrinsically Disordered Region Governs Small RNA Selectivity in Argonaute Proteins

Ida J. Isolehto, Lizaveta Pshanichnaya, Diego Javier Páez-Moscoso…·René F. Ketting

The paper identifies a novel regulatory mechanism involving proteolytic processing of N-terminal intrinsically disordered regions in C. elegans Argonaute proteins, which controls small RNA selectivity and activity.

DOI 10.64898/2025.12.19.695459

C. elegansprotein structure

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Molecular BiologybioRxivPreprintApr 23, 2024

Regulation of Microprocessor assembly and localization via Pasha's WW domain in C. elegans

Brooke E Montgomery, Thiago L. Knittel, Kailee J. Reed…·Taiowa A. Montgomery

The paper identifies residues in Pasha's WW domain critical for Microprocessor assembly and localization in C. elegans.

2 citations

C. elegansexperimental assay

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Developmental BiologyPLoS GeneticsPeer-reviewedJun 3, 2022

The Caenorhabditis elegans TDRD5/7-like protein, LOTR-1, interacts with the helicase ZNFX-1 to balance epigenetic signals in the germline

Elisabeth A. Marnik, Miguel Vasconcelos Almeida, Patricia Giselle Cipriani…·Dustin L. Updike

The paper identifies LOTR-1, a C. elegans protein with LOTUS and Tudor domains, which interacts with ZNFX-1 to regulate small RNA processing in the germline.

25 citations

C. elegansproteomics

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