Author

Qingtian Gong

University of St AndrewsORCID 0009-0002-8301-395XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Clarissa Melo CzeksteriD· 2 shared Aisling Lynch· 1 shared Carlin HamilliD· 1 shared Christopher John HardingiD· 1 shared John R. F. B. ConnollyiD· 1 shared Marc C. DevocelleiD· 1 shared Megan BergkesseliD· 1 shared Neeladri Sekhar Roy· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Clarissa Melo CzeksterORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 10, 2026

Structural basis for autoinhibition and self-activation in the Pseudomonas aeruginosa virulence factor protease IV (PIV)

Christopher John Harding, Carlin Hamill, Qingtian Gong, Clarissa Melo Czekster

This study determines the crystal structure of PIVS409A, revealing how the Cap region autoinhibits PIV and how it becomes activated through an intramolecular process.

DOI 10.64898/2026.09.07.749839

bacteria (other)protein structure

𝕏 PostBluesky

MicrobiologyACS Infectious DiseasesPeer-reviewedAug 20, 2026

Bacterial Aminopeptidase-Activated Peptide Prodrug Enables Species-Selective Targeting of Pseudomonas aeruginosa

Qingtian Gong, Silvia A. Synowsky, Aisling Lynch…·Clarissa Melo Czekster

This paper designs and tests aminopeptidase-activated AMP prodrugs that selectively target Pseudomonas aeruginosa, showing improved antimicrobial activity and reduced cross-resistance.

DOI 10.1021/acsinfecdis.6c00281

experimental assaydrug response / drug discovery

𝕏 PostBluesky