Long‐Sheng Song

This study shows that PHB complex ablation in cardiomyocytes leads to mTORC1 activation and metabolic reprogramming, causing dilated cardiomyopathy and mortality in mice.

This study identifies early aging-related changes in muscle MERC ultrastructure and proteome, which are reversed by exercise, suggesting potential therapeutic targets for sarcopenia.

This study shows junctophilin-2 protects cardiomyocytes from stress by preventing junctin ubiquitination and degradation, maintaining Ca2+ homeostasis and reducing apoptosis.

This study identifies GILT's role in maintaining cardiac immuno-metabolic homeostasis, showing its deficiency leads to heart failure in mice.

The paper identifies a micropeptide encoded by a long noncoding RNA that regulates pancreatic β-cell function and insulin secretion.

This study shows that O-GlcNAcylation and oxidative stress via CaMKII contribute to atrial fibrillation in type 1 and type 2 diabetes through distinct mechanisms.