Sylvia S. Sanchez

This study shows perinatal exposure to heavy metals and their mixtures alters cardiac gene expression, cellular composition, and immune signaling in a sex-specific manner in mice.

This study examines gene expression changes in fetal liver, heart, lung, and placenta after prenatal arsenic exposure in mice, identifying immune-related pathway alterations and reduced Gbp3 expression in female placentas.

Perinatal exposure of mice to a Pb, As, Cd and Cr(VI) mixture at EPA levels impaired recognition memory, raised anxiety-like behavior, and altered mPFC neuron function.

This study shows that low-dose inorganic arsenic exposure reprograms macrophage polarization, increasing tumor-promoting activity and altering immune responses in a sex-dependent manner.