Benedict J. Chambers

The paper uses spatial and single-cell techniques to show T and B cell clonal expansion in CXCL9-rich niches of sinonasal cancer, linking immune hubs to tumor regions.

The paper shows JAML expression on NK cells is regulated by tumor microenvironment and MHC class I interaction, with implications for NK cell-mediated tumor killing.

The paper shows that in a PCOS-like mouse model, altered uterine NK cells contribute to implantation failure through disrupted maturation and compensatory changes in NK cell subsets.

This study develops DARPin T cell engagers that specifically target HLA/peptide complexes on tumor cells, showing high affinity and specificity through in vitro selection and structural analysis.