Noèlia Fernàndez-castillo A

The paper identifies sex-specific miRNA signatures in the medial prefrontal cortex associated with cannabinoid addiction-like behavior in female mice.

This study shows that rbfox1 loss of function in zebrafish disrupts stress-related gene expression and increases cortisol levels during development, leading to behavioral and physiological signs of allostatic overload in adulthood.

This study investigates SUD heterogeneity by analyzing polygenic scores for psychiatric traits and their interactions with environmental factors in a deeply phenotyped SUD cohort.

This study identifies pleiotropic effects of dopaminergic and serotonergic genes on addiction, aggression, and related behaviors through GWAS and TWAS analyses across multiple datasets.

This study investigates the behavioral effects of rbfox1 deficiency in zebrafish, finding multiple behavioral changes that resemble those in Rbfox1-deficient mice and psychiatric patients.

This study shows that ywhaz gene deficiency in zebrafish affects brain activity and behavior, with altered neuronal connectivity and monoamine levels.

This study investigates the genetic contribution of dopaminergic and serotonergic pathways to eight psychiatric disorders using GWAS data from the Psychiatric Genomics Consortium.

This study identifies dopaminergic signaling as a genetic link between ADHD and obesity through genome-wide analyses and brain volume associations.

This study identifies three novel genes associated with ADHD by linking genetic variants to differential DNA methylation and gene expression in brain tissues.

The paper investigates the role of inherited and de novo truncating mutations in high functioning autism and identifies pleiotropic effects of LRP1 variants across psychiatric phenotypes.

This paper conducts a genome-wide association study of cocaine dependence, finding shared genetic risk factors with comorbid psychiatric conditions.