Naru Sato

This study shows that decitabine treatment increases CD112 expression in AML cells, which reduces NK cell-mediated cytotoxicity through the CD112-TIGIT/PVRIG axis, suggesting a strategy to enhance antileukemic activity by blocking this axis.

This study shows that ASXL1 mutations in mice promote atherosclerosis by dysregulating innate immunity through impaired inhibition of NF-κB signaling.