Author

Gregory J. Bedwell

Dana-Farber Cancer InstituteORCID 0000-0003-0456-0032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alan N. EngelmaniD· 2 shared Parmit Kumar SinghiD· 2 shared Rajalingam RadhakrishnaniD· 2 shared Abhishek Anand· 1 shared Adarsh DharaniD· 1 shared Ali Rabi· 1 shared Caroline EsnaultiD· 1 shared Edward M. CampbelliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Alan N. EngelmanORCID

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2 papers

Recent·Most cited

Cancer BiologyPLoS PathogensPeer-reviewedJan 17, 2025

The nuclear localization signal of CPSF6 governs post-nuclear import steps of HIV-1 infection

Nicholas Rohlfes, Rajalingam Radhakrishnan, Parmit Kumar Singh…·Edward M. Campbell

This study investigates how the nuclear localization signal (NLS) of CPSF6 influences HIV-1 infection after nuclear import, showing that some NLSs impair viral integration.

8 citations

humanexperimental assay

𝕏 PostBluesky

GenomicsbioRxivPreprintJun 29, 2024

The role of LEDGF in transcription is exploited by HIV-1 to position integration

Rakesh Pathak, Caroline Esnault, Rajalingam Radhakrishnan…·Henry L. Levin

This study shows LEDGF is recruited to promoters by MLL1 and recruits RNA Pol II, facilitating HIV-1 integration across gene bodies.

1 citation

humanChIP-seq

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