Alejandro Montilla

This study shows that IRF5 regulates microglial myelin clearance and cholesterol metabolism after demyelination, with implications for remyelination in multiple sclerosis.

The paper shows that depleting microglia and meningeal macrophages delays the onset of EAE by reducing antigen presentation and T cell reactivation.

This study shows clemastine increases oligodendrocyte differentiation but impairs myelination during development, likely due to microglia-oligodendrocyte interactions.