Mara H. Cowen

This study identifies conserved autism-associated genes that regulate social feeding behavior in C. elegans through distinct synaptic mechanisms.

This study shows that VPA exposure alters chromatin environment, leading to changes in alternative splicing and gene expression in human cortical neurons, which may contribute to ASD pathogenesis.

The paper uses iPSC-derived neurons from Christianson syndrome patients to show allele-specific responses to rescue strategies, highlighting the need for personalized therapeutic approaches.

This study shows ASH1L regulates neuronal connectivity by modulating BDNF/TrkB signaling through its interaction with PRC2 in human neurons, linking ASH1L mutations to autism pathogenesis.