Author

Victoria A. Trinkaus

Max Planck Institute of BiochemistryORCID 0000-0001-8964-6120Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

F. Ulrich HartliD· 2 shared Patricia Yuste‐ChecaiD· 2 shared Ana GalesiciD· 1 shared Anja DeiseriD· 1 shared Barbara HummeliD· 1 shared Carina Fernandez GonzaleziD· 1 shared Cole S. SitroniD· 1 shared Dennis FeigenbutziD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

F. Ulrich HartlORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 5, 2025

Mitochondrial proteostatic stress disrupts mitoribosome biogenesis and translation

Hauke Holthusen, Victoria A. Trinkaus, Carina Fernandez Gonzalez…·F. Ulrich Hartl

This study shows that proteostatic stress in mitochondria impairs mitoribosome biogenesis and translation, leading to respiratory deficiency and mitochondrial DNA loss.

1 citation

yeasthuman

𝕏 PostBluesky

BiochemistryMolecular CellPeer-reviewedSep 1, 2025

Alpha-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation

Cole S. Sitron, Victoria A. Trinkaus, Ana Galesic…·F. Ulrich Hartl

This study shows that alpha-synuclein fibrils sequester and degrade ESCRT-III proteins, leading to endolysosomal damage and increased alpha-synuclein aggregation.

17 citationstop 1%

humanproteomics

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