Author

Joaquı́n Pastor

Spanish National Cancer Research CentreORCID 0000-0003-0553-8021Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Alicia G. Serrano· 2 shared Gema López-PernasiD· 2 shared Marta Elena Antón· 2 shared Matilde MurgaiD· 2 shared Óscar Fernández-CapetilloiD· 2 shared Belén Navarro‐GonzáleziD· 1 shared Brinton A. Seashore-LudlowiD· 1 shared Carlota Cardona· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Alicia G. Serrano

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 29, 2025

The tyrosine kinase inhibitor GNF-7 targets senescent cells through allosteric activation of GCN2.

Gema López-Pernas, Matilde Murga, Wareed Ahmed…·Óscar Fernández-Capetillo

This study identifies GNF-7 as a senolytic drug that activates GCN2 to kill senescent cells, showing synergy with CDK4/6 inhibitors in preclinical models.

DOI 10.1101/2025.08.29.673062

humanmouse

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Cancer BiologyCell Death and DiseasePeer-reviewedSep 28, 2024

SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis

Matilde Murga, Gema López-Pernas, Robert Soliva…·Óscar Fernández-Capetillo

This study identifies novel SETD8 inhibitors and shows their toxicity correlates with ribosome biogenesis regulators, suggesting a biomarker for targeted cancer therapy.

6 citations

humanproteomics

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