Adriana Adolfi

This paper introduces a 3D HepG2/C3A liver spheroid model that supports the complete intrahepatocytic lifecycle of Plasmodium falciparum, offering an accessible and reproducible alternative to existing models.

The paper generates a high-quality genome assembly for Anopheles stephensi, identifies novel genomic features, and reveals hidden genetic elements contributing to insecticide resistance and male development.

This paper develops a gene-drive rescue system in Anopheles stephensi to efficiently modify mosquito populations for malaria control.

This paper functionally validates three genes associated with insecticide resistance in Anopheles gambiae by overexpressing them in transgenic mosquitoes and showing their role in resistance to different insecticide classes.