Ethan Bier

The paper identifies Rp-vasa as a primordial germ cell marker in Rhodnius prolixus and demonstrates its utility for gene expression in transgenic approaches.

This paper demonstrates successful gene editing in Rhodnius prolixus using ReMOT Control and DIPA-CRISPR methods, achieving mutations in eye and cuticle color genes.

This study shows that neuropeptides regulate intestinal integrity and aging in invertebrates, with effects modulated by the germline.

This study shows that meiotic Cas9 expression can mediate genotype conversion in both male and female mouse germlines, but low Cas9 levels limit efficiency.

The paper demonstrates a convertible gene-drive system that transitions from a split-drive to a full-drive element in the spo11 locus, showing similar final introgression levels despite initial slower kinetics.

This study tests split gene-drive systems in Drosophila that target essential genes, showing variable copy efficiencies and sex-biased transmission, with outcomes that can be inherently confined.

The paper generates a high-quality genome assembly for Anopheles stephensi, identifies novel genomic features, and reveals hidden genetic elements contributing to insecticide resistance and male development.

This paper develops a gene-drive rescue system in Anopheles stephensi to efficiently modify mosquito populations for malaria control.

The paper introduces a split-gene-drive system that enhances safety and flexibility in CRISPR-based gene drive applications through trans-complementation.

This study evaluates a split homing gene drive in Drosophila to simultaneously target two genes, showing high disruption efficiency but also resistance allele accumulation.

This paper demonstrates that CRISPR/Cas9 can mediate super-Mendelian inheritance in female mouse germline through homology-directed repair.

The paper shows that N-glycosylation of Sog in Drosophila affects BMP signaling by controlling extracellular Sog levels and distribution, adding complexity to BMP regulation.