Gareth John Lycett

This study shows that combining different molecular mechanisms increases insecticide resistance in Anopheles gambiae, with implications for resistance management.

This study assesses cross-resistance to transfluthrin in mosquitoes, showing resistance mechanisms reduce its efficacy in vector control.

The paper develops a synthetic biology approach to modulate gene expression in mosquitoes by systematically characterizing modifications in translation initiation sequences and 3' UTRs.

This study functionally validates the L1014F kdr mutation's role in pyrethroid resistance in Anopheles gambiae and shows its interaction with detoxification enzymes.

This paper functionally validates three genes associated with insecticide resistance in Anopheles gambiae by overexpressing them in transgenic mosquitoes and showing their role in resistance to different insecticide classes.

The paper develops a Gal4 driver line to fluorescently tag Anopheles gambiae oenocytes and shows two cyp4g genes are required for cuticular hydrocarbon synthesis.

The paper presents an improved Aedes aegypti genome assembly, AaegL5, which enhances biological understanding and vector control efforts by resolving key genomic features and identifying new targets for intervention.