Author

Claire H Caygill

Liverpool School of Tropical MedicineORCID 0000-0002-5546-9346Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:non-human primate· 1

Frequent Co-Authors

Giancarlo A. BiaginiiD· 2 shared Shaun H. PenningtoniD· 2 shared Adam WesthorpeiD· 1 shared Adam Winrow· 1 shared Adriana AdolfiiD· 1 shared Aitor Casas-SáncheziD· 1 shared Andrew OweniD· 1 shared Angelika SturmiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersMicrobiology

Giancarlo A. BiaginiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Establishment of snake venom gland organoids from a novel family, Colubridae

Stephanie A. French, Rachael Da Silva, Rohit N. Patel, Claire H Caygill, Shannon Quek, Adam Westhorpe, Jens Puschhof, Rebecca J. Edge, Charlotte A. Dawson, Edouard Crittenden, Paul D. Rowley, Zachary Holland, Stephen P. Mackessy, Cassandra Marie Modahl

This study establishes venom gland organoids from Colubridae snakes and shows in vitro toxin production.

bioRxiv · Mar 31, 2026 · PreprintBioengineering

Dynamic Culture Improves the Predictive Power of Bronchial and Alveolar Airway Models of SARS-CoV-2 Infection

Claire H Caygill, Rose C. Lopeman, Kirstie A Lewis, Emily Richardson, Aitor Casas-Sánchez, Nick Heavey, Adam Winrow, Louise Howard, Chris Williams, Dominic Wooding, Thomas Edwards, Eric R. Lucas, Tomasz M. Kostrzewski, Andrew Owen, Shaun H. Pennington, Giancarlo A. Biagini

This study compares static and dynamic flow culture conditions in human airway models to show that dynamic flow improves tissue architecture, infection dynamics, and predictive power for SARS-CoV-2 infection.

bioRxiv · Jul 21, 2025 · PreprintMicrobiology

An Accessible 3D HepG2/C3A Liver Spheroid Model Supporting the Complete Intrahepatocytic Lifecycle of Plasmodium falciparum

Claire H Caygill, Salwa Omar Alqurashi, Adriana Adolfi, Jessica Carson, Angelika Sturm, Daniel S. Evans, Jessica Jinks, Koen J. Dechering, Lisa J. Reimer, Shaun H. Pennington, Parveen Sharma, Stephen Andrew Ward, Giancarlo A. Biagini

This paper introduces a 3D HepG2/C3A liver spheroid model that supports the complete intrahepatocytic lifecycle of Plasmodium falciparum, offering an accessible and reproducible alternative to existing models.

Parasitology · Jun 20, 2025Peer-reviewedMicrobiology