Author

Kyle D. Duncan

University of VictoriaORCID 0000-0003-0575-0858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Joseph MonaghaniD· 2 shared Julian J. LumiD· 2 shared Tian ZhaoiD· 2 shared Bo-Hyun Kim· 1 shared David R. GoodlettiD· 1 shared Emily Mahony· 1 shared Gillian A. CarletoniD· 1 shared Helena PětrošováiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Joseph MonaghanORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 5, 2025

Ambient mass spectrometry imaging enables spatial metabolomics of optimal cutting temperature compound (OCT)-embedded tumors

Joseph Monaghan, Nicholas Woytowich, Tian Zhao…·Kyle D. Duncan

This paper demonstrates ambient mass spectrometry imaging of metabolites in OCT-embedded tumors, revealing spatial metabolic changes in a preclinical model.

1 citation

mousemetabolomics

ImmunologybioRxivPreprintOct 3, 2025

Methionine regulates antitumor function of CD8⁺ T cells through polyamine synthesis

Tian Zhao, Gillian A. Carleton, Sarah MacPherson…·Julian J. Lum

This study shows that methionine restriction affects CD8+ T cell function through polyamine synthesis, but does not improve antitumor efficacy in vivo.

3 citations

mousebulk RNA-seq