Tian Zhao

This study shows that mitochondrial proteostasis stress causes a biphasic cortisol response, with mild stress increasing and severe stress decreasing cortisol production, linking mitochondrial function to steroidogenesis in Parkinson's disease models.

This paper demonstrates ambient mass spectrometry imaging of metabolites in OCT-embedded tumors, revealing spatial metabolic changes in a preclinical model.

This study shows that methionine restriction affects CD8+ T cell function through polyamine synthesis, but does not improve antitumor efficacy in vivo.

The paper identifies PISD as a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes through exome sequencing and functional analysis of patient fibroblasts.

This study shows that SDHB deficiency reprograms energy metabolism and protects against high fat diet-induced obesity by restoring glucose and lipid metabolism.