Author
University of LuxembourgORCID 0000-0003-0575-156XUnclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Jun Yin, Maya L. Gosztyla, Birkan Gökbağ…·Robert T. Fremeau
The paper introduces scGENet, a framework to generate interpretable gene networks from single-cell foundation models, revealing conserved neurogenic dysfunction in Parkinson's disease.
Elisa Zuccoli, Haya Al Sawaf, Mona Tuzza…·Jens Christian Schwamborn
This study evaluates the reproducibility of midbrain organoid data from healthy individuals and GBA-N370S PD patients across batches and time points, showing consistent transcriptomic and metabolic signatures.
Sònia Sabaté‐Soler, Sarah Nickels, Cláudia Saraiva…·Jens Christian Schwamborn
This study integrates human iPSC-derived microglia into midbrain organoids, enhancing neuronal maturation and functionality through effects on synaptic remodeling and excitability.
Jennifer Modamio, Cláudia Saraiva, Gemma Gomez‐Giro…·Jens Christian Schwamborn
This study uses patient-specific midbrain organoids with SNCA triplication to show synaptic decline precedes dopaminergic neuron loss in Parkinson's disease.
Edinson Lucumi Moreno, Siham Hachi, Sarah Nickels…·Ronan M. T. Fleming
This study investigates neuronal activity in LRRK2-G2019S mutant neurons and finds increased spontaneous calcium transients and shorter inter-spike intervals.