Author

Alicia Garcia-Gimenez

Wellcome/MRC Cambridge Stem Cell InstituteORCID 0000-0003-0604-3215Unclaimed ORCID profile · follow to get notified of new preprints

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Albert KoulmaniD· 1 shared Benjamin JenkinsiD· 1 shared Brian J.P. HuntlyiD· 1 shared Cécile K. LopeziD· 1 shared David O’ConnoriD· 1 shared Dhoyazan AzaziiD· 1 shared Eshwar MeduriiD· 1 shared George GiotopoulosiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Albert KoulmanORCID

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1 paper

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedMay 20, 2025

Genetic or pharmacological inactivation of CREBBP sensitizes B-cell Acute Lymphoblastic Leukemia to Ferroptotic Cell Death upon BCL2 Inhibition

Alicia Garcia-Gimenez, Jonathan E. Ditcham, Dhoyazan Azazi…·Simon E. Richardson

This study identifies CREBBP mutations as a targetable vulnerability in B-ALL, showing that CREBBP inhibition sensitizes these cells to Venetoclax-induced ferroptosis.

19 citationstop 1%

humanbulk RNA-seq

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