Author

Laura C. Geben

Vanderbilt UniversityORCID 0000-0003-0604-4808Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

Rebecca A. IhrieiD· 3 shared Asa A. BrockmaniD· 2 shared Jonathan Michael IrishiD· 2 shared Kevin C. EssiD· 2 shared Mary‐Bronwen L. ChalkleyiD· 2 shared Aleksandar Krbanjevic· 1 shared Alexandra L. Scheuing· 1 shared Bret C. MobleyiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersSystems Biology

Rebecca A. IhrieORCID

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3 papers

Recent·Most cited

Systems BiologyCommunications BiologyPeer-reviewedJul 31, 2025

Single Cell Profiling Distinguishes Leukemia-Selective Chemotypes

Hannah L. Thirman, Madeline Hayes, Laura C. Geben…·Jonathan Michael Irish

The paper screens a compound library to identify leukemia-selective chemotypes using single-cell profiling and finds that certain rocaglate derivatives selectively induce DNA damage in leukemia cells.

3 citations

humanbulk RNA-seq

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NeuroscienceCytometry Part B Clinical CytometryPeer-reviewedJul 2, 2024

Multiparameter Quantitative Analyses of Diagnostic Cells in Brain Tissues from Tuberous Sclerosis Complex

Jerome S. Arceneaux, Asa A. Brockman, Rohit Khurana…·Rebecca A. Ihrie

The paper develops a machine learning tool to identify balloon cells in TSC brain tissues using imaging mass cytometry and a custom antibody panel.

6 citations

humanspatial transcriptomics

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Developmental BiologybioRxivPreprintFeb 14, 2023

Dephosphorylation of 4EBP1/2 Induces Prenatal Neural Stem Cell Quiescence

Laura C. Geben, Asa A. Brockman, Mary‐Bronwen L. Chalkley…·Rebecca A. Ihrie

This study identifies the role of 4EBP1/2 dephosphorylation in inducing quiescence in embryonic neural stem cells, offering insights into adult brain development and potential therapeutic strategies.

2 citations

mouseexperimental assay

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