GeneticsMolecular MetabolismPeer-reviewed
Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster
Nader H. Mahmoudzadeh, Yasaman Heidarian, Jason P. Tourigny…·Jason M. Tennessen
This study shows that L2hgdh in Drosophila renal tubules prevents L-2HG accumulation, supports mitochondrial metabolism, and enables hypoxia tolerance.
5 citations