Author

Stephen D. Fox

Frederick National Laboratory for Cancer ResearchORCID 0000-0003-0664-9970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Arun Prakash MishraiD· 1 shared Dillon Dierman· 1 shared Satheesh Kumar SengodaniD· 1 shared Shyam K. SharaniD· 1 shared Suhas S. KharatiD· 1 shared Walter ChaziniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Arun Prakash MishraORCID

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1 paper

Recent·Most cited

5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells

Suhas S. Kharat, Arun Prakash Mishra, Satheesh Kumar Sengodan, Dillon Dierman, Stephen D. Fox, Walter Chazin, Shyam K. Sharan

This study shows that 5hmC increases PARP1 trapping on chromatin in olaparib-treated cells, restoring PARP inhibitor sensitivity in BRCA1/2-deficient cancer cells.

Journal of Biological Chemistry · Jun 19, 2025Peer-reviewedCancer Biology