Kara L. Cerveny

The paper investigates how optic nerve innervation affects Wnt/b-catenin pathway activity and progenitor cell proliferation in zebrafish optic tectum, showing that innervation promotes survival and proliferation even in darkness.

This study shows that the GINS complex is essential for DNA replication in rapidly dividing retinal and tectal progenitor cells in zebrafish, leading to apoptosis in these cells when GINS function is absent.

The paper shows that mutant cells with cell cycle defects either die or differentiate in wild-type environments, while hyperproliferative cells form tumor-like structures and resist differentiation.

This study identifies Slbp as essential for cell cycle exit and neuronal differentiation in zebrafish, leading to retinal and brain defects.