Synaptotagmin-7 is required for synchronous but not asynchronous facilitation of glutamate release at cortical boutons
Dimitris Kotzadimitriou, Helen Langley, Eleanor McGowan…·Kirill E. Volynski
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UCL Queen Square Institute of NeurologyORCID 0000-0003-0704-5511Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Dimitris Kotzadimitriou, Helen Langley, Eleanor McGowan…·Kirill E. Volynski
Philipe R. F. Mendonça, Erica Tagliatti, Helen Langley…·Kirill E. Volynski
The paper quantifies asynchronous glutamate exocytosis in synapses, showing it is enhanced in low release probability synapses and more widely dispersed than synchronous release.
Erica Tagliatti, Oscar Daniel Bello, Philipe R. F. Mendonça…·Kirill E. Volynski
This study shows that Syt1 oligomerisation is essential for clamping spontaneous and asynchronous neurotransmitter release, revealing a mechanism for regulating release modes.
Gareth T. Banks, Mathilde C. C. Guillaumin, Ines Heise…·Patrick M. Nolan
This study identifies a Vamp2 mutation in mice that causes sleep-wake transition deficits by reducing synaptic release probability.