Synaptotagmin-7 is required for synchronous but not asynchronous facilitation of glutamate release at cortical boutons
Dimitris Kotzadimitriou, Helen Langley, Eleanor McGowan…·Kirill E. Volynski
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University of WarwickORCID 0000-0003-3178-7830Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
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Dimitris Kotzadimitriou, Helen Langley, Eleanor McGowan…·Kirill E. Volynski
Dipayan Bose, Manindra Bera, Christopher A. Norman…·Shyam Sundar Krishnakumar
The paper identifies a minimal set of presynaptic proteins that regulate different modes of Ca2+-triggered vesicle fusion and short-term plasticity.
Juliette Courson, Mathias Quoy, Yulia Timofeeva, Thanos Manos
This study uses computational models to explore seizure onset and propagation in mice brains and identifies strategies to limit seizure spread.
Philipe R. F. Mendonça, Erica Tagliatti, Helen Langley…·Kirill E. Volynski
The paper quantifies asynchronous glutamate exocytosis in synapses, showing it is enhanced in low release probability synapses and more widely dispersed than synchronous release.
Juliette Boeri, Claude Meunier, Hervé Le Corronc…·Antonny Czarnecki
The paper identifies two voltage-dependent currents that regulate the functional diversity and developmental trajectory of embryonic Renshaw cells.
Robert P. Gowers, Yulia Timofeeva, Magnus J. E. Richardson
The paper develops an analytical framework to approximate neuronal firing rates in spatially extended neurons with dendrites, soma, and axon, showing how spatial structure affects firing properties.
Erica Tagliatti, Oscar Daniel Bello, Philipe R. F. Mendonça…·Kirill E. Volynski
This study shows that Syt1 oligomerisation is essential for clamping spontaneous and asynchronous neurotransmitter release, revealing a mechanism for regulating release modes.
Simon Chamberland, Yulia Timofeeva, Alesya Evstratova…·Katalin Tóth
The paper demonstrates that mossy fibers count action potentials to transmit information to CA3 pyramidal neurons through presynaptic calcium dynamics and vesicle replenishment.