Author

Thoudam Debraj Singh

DR. B.R.A. Institute Rotary Cancer HospitalORCID 0000-0003-0750-9136Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1 Assay:metabolomics· 1

Frequent Co-Authors

Aditya GuptaiD· 3 shared Baibaswata NayakiD· 3 shared Deepam PushpamiD· 3 shared Hridayesh PrakashiD· 3 shared Manoranjan MahapatraiD· 3 shared Meenakshi MendirattaiD· 3 shared Mohini MendirattaiD· 3 shared Mukul AggarwaliD· 3 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Aditya GuptaORCID

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Author profile →

3 papers

Recent·Most cited

Dual Preconditioned Mesenchymal Stem Cells-Derived Culture Conditioned Media Augment Immunomodulation and Drive Metabolic Reprogramming in Acute Graft-versus-Host Disease

Mohini Mendiratta, Meenakshi Mendiratta, Sandeep Rai, Ritu Gupta, Sameer Bakhshi, Vatsla Dadhwal, Deepam Pushpam, Prabhat Singh Malik, Raja Pramanik, Mukul Aggarwal, Aditya Gupta, Rishi Dhawan, Tulika Seth, Manoranjan Mahapatra, Baibaswata Nayak, , Ranjit Kumar Sahoo

bioRxiv · Nov 2, 2025 · PreprintImmunology

Hypoxia-Mediated Molecular Interactions of Tissue-Specific Mesenchymal Stem Cells Drive Metabolic Reprogramming and Immunomodulation in Acute Graft-versus-Host Disease

Mohini Mendiratta, Meenakshi Mendiratta, Lakshay Malhotra, Sandeep Rai, Vijaya Sarangathem, Prince Dahiya, Ritu Gupta, Sameer Bakhshi, Vatsla Dadhwal, Deepam Pushpam, Mukul Aggarwal, Aditya Gupta, Prabhat Singh Malik, Raja Pramanik, Manoranjan Mahapatra, , Ranjit Kumar Sahoo

This study compares the immunomodulatory effects of hypoxia-preconditioned bone marrow and Wharton's jelly mesenchymal stem cells in acute graft-versus-host disease, finding WJ-MSCsHYP more effective due to enhanced mitochondrial transfer and metabolic reprogramming.

bioRxiv · Jan 6, 2025 · PreprintImmunology

Synergistic Hypoxia and Apoptosis Conditioning Unleashes Superior Mesenchymal Stem Cells Efficacy in Acute Graft-versus-Host-Disease

Mohini Mendiratta, Meenakshi Mendiratta, Shuvadeep Ganguly, Sandeep Rai, Ritu Gupta, Lalit Kumar, Sameer Bakhshi, Vatsla Dadhwal, Deepam Pushpam, Prabhat Singh Malik, Raja Pramanik, Mukul Aggarwal, Aditya Gupta, Rishi Dhawan, Tulika Seth, , Ranjit Kumar Sahoo

This study shows that hypoxia and apoptosis conditioning of WJ-MSCs enhances their immune regulatory capacity in aGVHD by promoting Treg differentiation and M2 macrophage polarization.

Stem Cell Research & Therapy · Oct 29, 2024Peer-reviewedImmunology