Molecular BiologyThe EMBO JournalPeer-reviewed
Single-molecule imaging reveals the interplay between transcription factors, nucleosomes, and transcriptional bursting
Benjamin T. Donovan, Anh Huynh, David A. Ball…·Tineke Laura Lenstra
This study uses single-molecule imaging to show that Gal4 dwell time determines transcriptional burst size in yeast, with nucleosomes reducing dwell time and affecting transcriptional bursting kinetics.