Author

Cláudia C. Mendes

University of OxfordORCID 0000-0003-0761-5676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

CLIVE G. WILSONiD· 2 shared Deborah C. I. GoberdhaniD· 2 shared Adam Wells· 1 shared Adrian Llewellyn HarrisiD· 1 shared Alfina A. SpecialeiD· 1 shared André GörgensiD· 1 shared Bhavna VermaiD· 1 shared Dali DunniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

CLIVE G. WILSONORCID

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2 papers

Recent·Most cited

Cell BiologyThe EMBO JournalPeer-reviewedJul 17, 2025

APP and β-amyloid modulate protein aggregation and dissociation from recycling endosomal and exosomal membranes

Preman J Singh, Bhavna Verma, Adam Wells…·CLIVE G. WILSON

The paper shows APP and Aβ-peptides modulate protein aggregation and DCG biogenesis in Drosophila cells, with mutant Aβ-peptides disrupting these processes and causing AD-like pathologies.

10 citations

Drosophilaproteomics

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NeuroscienceNature CommunicationsPeer-reviewedNov 18, 2021

GAPDH controls extracellular vesicle biogenesis and enhances therapeutic potential of EVs in silencing the Huntingtin gene in mice via siRNA delivery

Ghulam Hassan Dar, Cláudia C. Mendes, Wei‐Li Kuan…·Matthew J. A. Wood

This study shows GAPDH facilitates EV biogenesis and enables efficient siRNA delivery to the brain, reducing huntingtin gene expression in a mouse model.

100 citationstop 3%

mousebulk RNA-seq

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